Silvia Lang Selected Research

Non-Receptor Type 22 Protein Tyrosine Phosphatase

12/2021	Loss of PTPN22 Promotes Intestinal Inflammation by Compromising Granulocyte-mediated Antibacterial Defence.
11/2019	Loss of PTPN22 abrogates the beneficial effect of cohousing-mediated fecal microbiota transfer in murine colitis.
1/2019	Protein tyrosine phosphatase non-receptor type 22 modulates colitis in a microbiota-dependent manner.
9/2017	PTPN22 regulates NLRP3-mediated IL1B secretion in an autophagy-dependent manner.
1/2013	Protein tyrosine phosphatase non-receptor type 22 modulates NOD2-induced cytokine release and autophagy.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Silvia Lang Research Topics

Disease

19	Colitis 01/2022 - 10/2013
13	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022 - 01/2013
11	Inflammation (Inflammations) 01/2022 - 01/2013
9	Crohn Disease (Crohn's Disease) 01/2022 - 01/2013
7	Fistula 01/2022 - 01/2013
7	Neoplasms (Cancer) 01/2022 - 01/2018
6	Fibrosis (Cirrhosis) 01/2022 - 01/2016
5	Ulcerative Colitis 11/2021 - 01/2013
4	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2019
3	Infections 01/2021 - 02/2011
2	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 09/2015
2	Hypoxia (Hypoxemia) 05/2021 - 10/2014
2	Rheumatoid Arthritis 01/2018 - 09/2017
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2018 - 09/2017
2	Neuroblastoma 01/2017 - 01/2016
1	Carcinoma (Carcinomatosis) 01/2022
1	Breast Neoplasms (Breast Cancer) 01/2022
1	Critical Illness (Critically Ill) 12/2021
1	Bezoars (Bezoar) 12/2021
1	Melanoma (Melanoma, Malignant) 10/2021
1	End Stage Liver Disease 01/2021
1	Autoimmune Diseases (Autoimmune Disease) 02/2019
1	Acidosis 02/2019
1	Triple Negative Breast Neoplasms 07/2018
1	Colonic Neoplasms (Colon Cancer) 01/2018

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2011
8	Dextrans (Dextran)FDA Link 01/2022 - 01/2017
8	Messenger RNA (mRNA)IBA 05/2019 - 01/2013
6	CytokinesIBA 09/2021 - 10/2013
6	Protein Tyrosine PhosphatasesIBA 06/2021 - 05/2013
5	Non-Receptor Type 22 Protein Tyrosine PhosphataseIBA 12/2021 - 01/2013
5	Dextran SulfateIBA 09/2021 - 10/2013
4	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2022 - 09/2015
4	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2022 - 01/2017
4	Interleukin-10 (Interleukin 10)IBA 12/2021 - 10/2014
4	SodiumIBA 05/2021 - 07/2017
4	Interleukin-13IBA 01/2021 - 01/2013
3	Interleukin-6 (Interleukin 6)IBA 09/2021 - 10/2014
3	EnzymesIBA 01/2019 - 01/2016
2	IntegrinsIBA 01/2022 - 01/2019
2	titanium dioxide (Titania)FDA Link 01/2021 - 01/2017
2	Non-Receptor Type 2 Protein Tyrosine PhosphataseIBA 01/2021 - 01/2018
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 12/2013
2	Transforming Growth Factor beta (TGF-beta)IBA 01/2021 - 12/2013
2	Drinking WaterIBA 01/2021 - 05/2019
2	InterleukinsIBA 01/2021 - 01/2013
2	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2015
2	InflammasomesIBA 01/2018 - 01/2017
2	Peroxidase (Myeloperoxidase)IBA 07/2017 - 10/2013
2	Everolimus FDA Link 01/2017 - 01/2016
2	Anthocyanins (Anthocyanin)IBA 01/2016 - 01/2014
2	RetinoidsIBA 10/2013 - 08/2013
2	Acetylmuramyl-Alanyl-IsoglutamineIBA 01/2013 - 01/2013
1	Protons (Proton)IBA 01/2022
1	Matrix Metalloproteinases (MMPs)IBA 01/2022
1	MicroplasticsIBA 01/2022
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2022
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2022
1	Keratin-8 (Keratin 8)IBA 01/2022
1	Programmed Cell Death 1 ReceptorIBA 01/2022
1	AntibodiesIBA 01/2022
1	PlasticsIBA 01/2022
1	Polystyrenes (Polystyrene)IBA 01/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2021
1	Sodium Bicarbonate (Baking Soda)FDA LinkGeneric 12/2021
1	Tacrolimus (Prograf)FDA LinkGeneric 11/2021
1	Immunomodulating AgentsIBA 11/2021
1	vedolizumabIBA 11/2021
1	Therapeutic UsesIBA 09/2021
1	Clodronic Acid (Clodronate)IBA 06/2021
1	Extracellular Matrix ProteinsIBA 05/2021
1	Food Additives (Food Additive)IBA 01/2021
1	Interleukin-22 (IL-22)IBA 01/2021
1	Alanine Transaminase (SGPT)IBA 01/2021
1	Antiviral Agents (Antivirals)IBA 01/2021
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2021
1	TransferasesIBA 01/2021
1	Granzymes (Granzyme)IBA 01/2021
1	Tight Junction ProteinsIBA 10/2019
1	Epidermal Growth Factor (EGF)IBA 10/2019
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2019
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 10/2019
1	AzoxymethaneIBA 05/2019
1	RNA (Ribonucleic Acid)IBA 02/2019
1	Carcinoembryonic AntigenIBA 01/2019
1	CCR10 ReceptorsIBA 01/2019
1	OxysterolsIBA 01/2019
1	Tumor Biomarkers (Tumor Markers)IBA 01/2019
1	Transcription Factors (Transcription Factor)IBA 07/2018
1	MacrolidesIBA 07/2018
1	eribulin FDA Link 07/2018
1	halichondrin BIBA 07/2018
1	Cadherins (E-Cadherin)IBA 09/2017
1	Peptides (Polypeptides)IBA 09/2017

Therapy/Procedure

7	Therapeutics 01/2022 - 01/2016
2	Immunotherapy 01/2022 - 01/2021
2	Aftercare (After-Treatment) 03/2016 - 10/2013
1	Fecal Microbiota Transplantation 11/2019
1	Transplantation 05/2019